SSRP1 抗体 (AA 2-381)
Quick Overview for SSRP1 抗体 (AA 2-381) (ABIN7600496)
抗原
See all SSRP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-381
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原理
- Anti-SSRP1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SSRP1 Antibody Picoband® (ABIN7600496). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SSRP1 recombinant protein (Position: A2-R381).
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亚型
- IgG
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anti-Structure Specific Recognition Protein 1 (SSRP1) antibody
SSRP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (AA 1-300) antibodySSRP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (AA 1-242) antibodySSRP1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodyKO Validated SSRP1 适用: 人 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (N-Term) antibodySSRP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人 WB 宿主: 小鼠 Monoclonal 10D7 unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人 WB 宿主: 小鼠 Monoclonal 3E4 unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (AA 611-660) antibodySSRP1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, Pig, 猴, Bat, Drosophila melanogaster, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Belotserkovskaya, R., Oh, S., Bondarenko, V. A., Orphanides, G., Studitsky, V. M., Reinberg, D. FACT facilitates transcription-dependent nucleosome alteration. Science 301: 1090-1093, 2003. 2. Bruhn, S. L., Pil, P. M., Essigmann, J. M., Housman, D. E., Lippard, S. J. Isolation and characterization of human cDNA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent cisplatin. Proc. Nat. Acad. Sci. 89: 2307-2311, 1992. 3. Keller, D. M., Zeng, X., Wang, Y., Zhang, Q. H., Kapoor, M., Shu, H., Goodman, R., Lozano, G., Zhao, Y., Lu, H. A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1. Molec. Cell 7: 283-292, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
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别名
- SSRP1
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背景
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Synonyms: Homeobox protein SIX3,Sine oculis homeobox homolog 3,SIX3,
Tissue Specificity: Highly expressed in placenta, lung, kidney, testis and ovary. Weakly expressed in spleen and thymus. Not expressed in peripheral blood lymphocytes. Detected in hippocampus.
Background: FACT complex subunit SSRP1 also known as structure specific recognition protein 1 is a protein that in humans is encoded by the SSRP1 gene. The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
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分子量
- 92 kDa
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基因ID
- 6749
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UniProt
- Q08945
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途径
- Chromatin Binding
抗原
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