NDRG1 抗体 (AA 2-220)
Quick Overview for NDRG1 抗体 (AA 2-220) (ABIN7600474)
抗原
See all NDRG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-220
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原理
- Anti-NDRG1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NDRG1 Antibody Picoband® (ABIN7600474). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NDRG1 recombinant protein (Position: S2-N220).
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亚型
- IgG
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anti-N-Myc Downstream Regulated 1 (NDRG1) (C-Term) antibody
Verified NDRG1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-N-Myc Downstream Regulated 1 (NDRG1) (AA 1-394) antibodyNDRG1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-N-Myc Downstream Regulated 1 (NDRG1) antibodyNDRG1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-N-Myc Downstream Regulated 1 (NDRG1) (AA 12-40) antibodyNDRG1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Downstream Regulated 1 (NDRG1) (AA 136-394) antibodyNDRG1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Downstream Regulated 1 (NDRG1) antibodyNDRG1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Monoclonal 4C8 unconjugated Recombinant Antibody
anti-N-Myc Downstream Regulated 1 (NDRG1) antibodyNDRG1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Downstream Regulated 1 (NDRG1) (AA 175-394) antibodyNDRG1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Downstream Regulated 1 (NDRG1) antibodyNDRG1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Downstream Regulated 1 (NDRG1) (AA 12-40), (N-Term) antibodyNDRG1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21832 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hunter, M., Bernard, R., Freitas, E., Boyer, A., Morar, B., Martins, I. J., Tournev, I., Jordanova, A., Guergelcheva, V., Ishpekova, B., Kremensky, I., Nicholson, G., Schlotter, B., Lochmuller, H., Voit, T., Colomer, J., Thomas, P. K., Levy, N., Kalaydjieva, L. Mutation screening of the N-myc downstream-regulated gene 1 (NDRG1) in patients with Charcot-Marie-Tooth disease. Hum. Mutat. 22: 129-135, 2003. 2. Okamoto, Y., Goksungur, M. T., Pehlivan, D., Beck, C. R., Gonzaga-Jauregui, C., Muzny, D. M., Atik, M. M., Carvalho, C. M. B., Matur, Z., Bayraktar, S., Boone, P. M., Akyuz, K., Gibbs, R. A., Battaloglu, E., Parman, Y., Lupski, J. R. Exonic duplication CNV of NDRG1 associated with autosomal-recessive HMSN-Lom/CMT4D. Genet. Med. 16: 386-394, 2014. Note: Erratum: Genet. Med. 16: 203 only, 2014. 3. Okuda, T., Higashi, Y., Kokame, K., Tanaka, C., Kondoh, H., Miyata, T. Ndrg1-deficient mice exhibit a progressive demyelinating disorder of peripheral nerves. Molec. Cell. Biol. 24: 3949-3956, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))
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别名
- NDRG1
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背景
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Synonyms: Protein NDRG1, Differentiation-related gene 1 protein, DRG-1, N-myc downstream-regulated gene 1 protein, Nickel-specific induction protein Cap43, Reducing agents and tunicamycin-responsive protein, RTP, Rit42, NDRG1, CAP43, DRG1, RTP
Tissue Specificity: Ubiquitous, expressed most prominently in placental membranes and prostate, kidney, small intestine, and ovary tissues. Also expressed in heart, brain, skeletal muscle, lung, liver and pancreas. Low levels in peripheral blood leukocytes and in tissues of the immune system. Expressed mainly in epithelial cells. Also found in Schwann cells of peripheral neurons. Reduced expression in adenocarcinomas compared to normal tissues. In colon, prostate and placental membranes, the cells that border the lumen show the highest expression.
Background: Protein NDRG1 is a protein that in humans is encoded by the NDRG1 gene. It is a member of the N-myc downregulated gene family which belong to the alpha/beta hydrolase superfamily. The NDRG1 gene is mapped to chromosome 8q24. It has got a deduced 394 amino acid protein with a molecular mass of 43kD. NDRG1 is expressed in the cytoplasm and basolateral membranes of gut lumen surface epithelial cells. The protein appears to play a vital role in growth arrest and cell differentiation.
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分子量
- 46 kDa
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基因ID
- 10397
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UniProt
- Q92597
抗原
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