IFT88 抗体 (AA 198-814)
Quick Overview for IFT88 抗体 (AA 198-814) (ABIN7600458)
抗原
See all IFT88 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 198-814
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原理
- Anti-IFT88 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-IFT88 Antibody Picoband® (ABIN7600458). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human IFT88 recombinant protein (Position: E198-K814).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cano, D. A., Murcia, N. S., Pazour, G. J., Hebrok, M. orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization. Development 131: 3457-3467, 2004. 2. Delaval, B., Bright, A., Lawson, N. D., Doxsey, S. The cilia protein IFT88 is required for spindle orientation in mitosis. Nature Cell Biol. 13: 461-468, 2011. 3. Huangfu, D., Liu, A., Rakeman, A. S., Murcia, N. S., Niswander, L., Anderson, K. V. Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature 426: 83-87, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IFT88 (Intraflagellar Transport 88 Homolog (IFT88))
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别名
- IFT88
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背景
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Synonyms: Intraflagellar transport protein 88 homolog, Recessive polycystic kidney disease protein Tg737 homolog, Tetratricopeptide repeat protein 10, TPR repeat protein 10, IFT88, TG737, TTC10
Tissue Specificity: Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas.
Background: Intraflagellar transport protein 88 homolog is a protein that in humans is encoded by the IFT88 gene. It is mapped to 13q12.11. This gene encodes a member of the tetratrico peptide repeat (TPR) family. The encoded protein is involved in cilium biogenesis. Mutations of a similar gene in mouse can cause polycystic kidney disease. Several transcript variants encoding distinct isoforms have been identified for this gene.
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分子量
- 94 kDa
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基因ID
- 8100
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UniProt
- Q13099
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途径
- Hedgehog Signaling, Sensory Perception of Sound
抗原
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