SENP1 抗体 (AA 19-619)
Quick Overview for SENP1 抗体 (AA 19-619) (ABIN7600423)
抗原
See all SENP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 19-619
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原理
- Anti-SENP1 Antibody Picoband® (monoclonal, 5F4)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SENP1 Antibody Picoband® (monoclonal, 5F4) (ABIN7600423). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SENP1 recombinant protein (Position: N19-P619).
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亚型
- IgG1
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anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (AA 220-420) antibody
SENP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (AA 63-214) antibodySENP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) antibodySENP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (AA 28-59), (N-Term) antibodySENP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0647 unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (AA 28-59) antibodySENP1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (C-Term) antibodySENP1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (AA 221-460) antibodySENP1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (N-Term) antibodySENP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (N-Term) antibodySENP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (AA 578-590) antibodySENP1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Veltman, I. M., Vreede, L. A., Cheng, J., Looijenga, L. H. J., Janssen, B., Schoenmakers, E. F. P. M., Yeh, E. T. H., Geurts van Kessel, A. Fusion of the SUMO/sentrin-specific protease 1 gene SENP1 and the embryonic polarity-related mesoderm development gene MESDC2 in a patient with an infantile teratoma and a constitutional t(12,15)(q13,q25). Hum. Molec. Genet. 14: 1955-1963, 2005. 2. Yamaguchi, T., Sharma, P., Athanasiou, M., Kumar, A., Yamada, S., Kuehn, M. R. Mutation of SENP1/SuPr-2 reveals an essential role for desumoylation in mouse development. Molec. Cell. Biol. 25: 5171-5182, 2005. 3. Yu, L., Ji, W., Zhang, H., Renda, M. J., He, Y., Lin, S., Cheng, E., Chen, H., Krause, D. S., Min, W. SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis. J. Exp. Med. 207: 1183-1195, 2010. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))
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别名
- SENP1
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背景
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Synonyms: Keratin, type I cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19, KRT19
Tissue Specificity: Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.
Background: Sentrin-specific protease 1 is a protein that in human is encoded by the SENP1 gene. This gene is mapped to 12q13.11. This gene encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript variants.
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分子量
- 73 kDa
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基因ID
- 29843
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UniProt
- Q9P0U3
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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