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SENP1 抗体 (N-Term)

SENP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264983
发货至: 中国
  • 抗原 See all SENP1 抗体
    SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))
    抗原表位
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 56
    • 21
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 67
    • 2
    克隆类型
    • 60
    • 9
    多克隆
    标记
    • 32
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SENP1 antibody is un-conjugated
    应用范围
    • 50
    • 34
    • 17
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    SENP1 Antibody detects endogenous levels of total SENP1.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human SENP1, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product SENP1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))
    别名
    SENP1 (SENP1 产品)
    别名
    SuPr-2 antibody, 2310046A20Rik antibody, D15Ertd528e antibody, E330036L07Rik antibody, suPr-2 antibody, senp1 antibody, senp1a antibody, xsenp1 antibody, SENP1 antibody, Senp1 antibody, senp1b antibody, SUMO1/sentrin specific peptidase 1 antibody, SUMO1/sentrin specific peptidase 1 S homeolog antibody, sentrin/SUMO-specific protease 1 antibody, SUMO1/sentrin specific peptidase 1 L homeolog antibody, SENP1 antibody, Senp1 antibody, senp1.S antibody, senp1.L antibody, senp1 antibody
    背景

    Description: Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. Deconjugates SUMO1 from HIPK2 (PubMed:16253240). Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity (PubMed:21829689). Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity (PubMed:23160374). Deconjugates SUMO2 from MTA1 (PubMed:21965678). Desumoylates CCAR2 which decreases its interaction with SIRT1 (PubMed:25406032). Deconjugates SUMO1 from GPS2 (PubMed:24943844).

    Gene: SENP1

    分子量
    73kDa
    基因ID
    29843
    UniProt
    Q9P0U3
    途径
    Positive Regulation of Endopeptidase Activity
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