SOS1 抗体 (AA 177-1288)
Quick Overview for SOS1 抗体 (AA 177-1288) (ABIN7600301)
抗原
See all SOS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 177-1288
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原理
- Anti-SOS1 Antibody Picoband®
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产品特性
- Anti-SOS1 Antibody Picoband® (ABIN7600301). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SOS1 recombinant protein (Position: H177-A1288). Human SOS1 shares 96.5% amino acid (aa) sequence identity with mouse SOS1.
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anti-Son of Sevenless Homolog 1 (SOS1) (AA 1140-1281) antibody
SOS1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Son of Sevenless Homolog 1 (SOS1) (AA 313-420) antibodySOS1 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 4C1 unconjugated
anti-Son of Sevenless Homolog 1 (SOS1) antibodySOS1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 小鼠 Monoclonal SOS-01 unconjugated
anti-Son of Sevenless Homolog 1 (SOS1) antibodySOS1 适用: 人, 小鼠 WB, IF, EIA 宿主: 小鼠 Monoclonal SOS-1 unconjugated
anti-Son of Sevenless Homolog 1 (SOS1) (AA 934-962) antibodySOS1 适用: 人 WB 宿主: 兔 Polyclonal RB23356 unconjugated
anti-Son of Sevenless Homolog 1 (SOS1) (AA 313-420) antibodySOS1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Son of Sevenless Homolog 1 (SOS1) (AA 353-402) antibodySOS1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Son of Sevenless Homolog 1 (SOS1) (AA 1034-1333) antibodySOS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bowtell, D., Fu, P., Simon, M. A., Senior, P. Identification of murine homologues of the Drosophila Son of sevenless gene: potential activators of ras. Proc. Nat. Acad. Sci. 89: 6511-6515, 1992. 2. Chardin, P., Camonis, J. H., Gale, N. W., Van Aelst, L., Schlessinger, J., Wigler, M. H., Bar-Sagi, D. Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2. Science 260: 1338-1343, 1993. 3. Ferrero, G. B., Baldassarre, G., Delmonaco, A. G., Biamino, E., Banaudi, E., Carta, C., Rossi, C., Silengo, M. C. Clinical and molecular characterization of 40 patients with Noonan syndrome. Europ. J. Med. Genet. 51: 566-572, 2008. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SOS1 (Son of Sevenless Homolog 1 (SOS1))
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别名
- SOS1
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背景
- Son of sevenless homolog 1 is a protein that in humans is encoded by the SOS1 gene. This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4.
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分子量
- 170 kDa
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基因ID
- 6654
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UniProt
- Q07889
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途径
- RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
抗原
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