SOS1 抗体
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北京 101111
Quick Overview for SOS1 抗体 (ABIN238504)
抗原
See all SOS1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody SOS-01 reacts with human Sos, an ubiquitously expressed 150 kDa intracellular protein.
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产品特性
- Synonyms: SOS-1, Son of sevenless homolog 1
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纯化方法
- Protein A affinity chromatography.
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免疫原
- Peptide corresponding to amino acids THPSMHRDGPPLLENAHSS of human Sos protein.
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亚型
- IgG1
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anti-Son of Sevenless Homolog 1 (SOS1) (AA 313-420) antibody
SOS1 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 4C1 unconjugated
anti-Son of Sevenless Homolog 1 (SOS1) (AA 1140-1281) antibodySOS1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Son of Sevenless Homolog 1 (SOS1) antibodySOS1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 小鼠 Monoclonal SOS-01 unconjugated
anti-Son of Sevenless Homolog 1 (SOS1) (AA 934-962) antibodySOS1 适用: 人 WB 宿主: 兔 Polyclonal RB23356 unconjugated
anti-Son of Sevenless Homolog 1 (SOS1) (AA 313-420) antibodySOS1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Son of Sevenless Homolog 1 (SOS1) (AA 353-402) antibodySOS1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Son of Sevenless Homolog 1 (SOS1) (AA 1034-1333) antibodySOS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blotting under reducing conditions (1 μg/mL): Positive control: HeLa human cervix carcinoma cell line. Immunocytochemistry. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4 with 15 mM sodium azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze/thaw cycles.
Shelf life: One year from despatch. -
有效期
- 12 months
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- SOS1 (Son of Sevenless Homolog 1 (SOS1))
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别名
- SOS1
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背景
- The guanine nucleotide exchange factor Sos (Son-of-sevenless) is a complex multidomain protein that activates the small GTPase Ras (H-Ras, K-Ras, N-Ras, but not functionally distinct R-Ras) in response to receptor tyrosine kinase stimulation. Nucleotide exchange activity of Sos is stimulated by allosteric Ras binding. By another (separable) guanine exchange factor domain domain Sos modulates activity of Rac/Rho GTPases. Sos thus integrates signals that affect both gene expression and cytoskeletal reorganization, the Sos-mediated Ras-activation and Rac activation differ in composition and stability of the formed complex.Synonyms: SOS-1, Son of sevenless homolog 1
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基因ID
- 6654
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UniProt
- Q07889
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途径
- RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
抗原
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