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Insulin Receptor 抗体 (AA 168-621)

This anti-Insulin Receptor antibody is a 兔 多克隆 antibody detecting Insulin Receptor in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7600241
发货至: 中国

Quick Overview for Insulin Receptor 抗体 (AA 168-621) (ABIN7600241)

抗原

See all Insulin Receptor (INSR) 抗体
Insulin Receptor (INSR)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 145
  • 80
多克隆

标记

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This Insulin Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 168-621

    原理

    Anti-Insulin Receptor/INSR Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Insulin Receptor/INSR Antibody (ABIN7600241). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Insulin Receptor/INSR recombinant protein (Position: E168-N621).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    Insulin Receptor (INSR)

    别名

    INSR

    背景

    Synonyms: RAF proto-oncogene serine/threonine-protein kinase,2.7.11.1,Proto-oncogene c-RAF,cRaf,Raf-1,RAF1,RAF,

    Tissue Specificity: In skeletal muscle, isoform 1 is more abundant than isoform 2. .

    Background: INSR(INSULIN RECEPTOR) is a tetramer of 2 alpha and 2 beta subunits that are coded by a single gene and are joined by disulfide bonds, a mechanism parallel to that of its ligand, insulin. It belongs to the large class of tyrosine kinase receptors. The insulin receptor gene is mapped to 19p13.2. The insulin receptor mediates their activity by causing the addition of a phosphate group to particular tyrosines on certain proteins within a cell. The INSR gene spans more than 120 kb and has 22 exons. Functional studies of the INSR SNPs show no effect on mRNA levels or splicing in peripheral blood leukocytes or on binding of insulin to mononuclear cells.

    分子量

    156 kDa

    基因ID

    3643

    UniProt

    P06213

    途径

    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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