CDK5RAP2 抗体 (AA 168-1878)
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- 抗原 See all CDK5RAP2 抗体
- CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))
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抗原表位
- AA 168-1878
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDK5RAP2 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 原理
- Anti-CDK5RAP2 Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-CDK5RAP2 Antibody Picoband® (ABIN7600238). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human CDK5RAP2 recombinant protein (Position: E168-P1878).
- 亚型
- IgG
- Top Product
- Discover our top product CDK5RAP2 Primary Antibody
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anti-CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2) (AA 996-1111), (Regulatory Subunit) antibody
CDK5RAP2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2) (AA 1744-1893) antibodyCDK5RAP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bond, J., Roberts, E., Springell, K., Lizarraga, S., Scott, S., Higgins, J., Hampshire, D. J., Morrison, E. E., Leal, G. F., Silva, E. O., Costa, S. M. R., Baralle, D., Raponi, M., Karbani, G., Rashid, Y., Jafri, H., Bennett, C., Corry, P., Walsh, C. A., Woods, C. G. A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size. Nature Genet. 37: 353-355, 2005. Note: Erratum: Nature Genet. 37: 555 only, 2005. 2. Ching, Y. P., Qi, Z., Wang, J. H. Cloning of three novel neuronal Cdk5 activator binding proteins. Gene 242: 285-294, 2000. 3. Evans, P. D., Vallender, E. J., Lahn, B. T. Molecular evolution of the brain size regulator genes CDK5RAP2 and CENPJ. Gene 375: 75-79, 2006. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))
- 别名
- CDK5RAP2 (CDK5RAP2 产品)
- 背景
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Synonyms: NADPH oxidase 5, NOX5
Tissue Specificity: Mainly expressed in pachytene spermatocytes of testis and in lymphocyte-rich areas of spleen and lymph nodes. Isoform v1 is expressed in spleen. Isoform v2 is expressed in testis. Also detected in ovary, placenta, pancreas, cardiac fibroblasts. Expressed in B-cells and prostate malignant cells. Isoform v1 and isoform v3 are expressed in epithelial colorectal adenocarcinoma cells. Isoform v2 and isoform v4 are expressed in endothelial cells. Isoform v1, isoform v2, isoform v3 and isoform v4 are expressed in pulmonary artery smooth muscle cells. Isoform v2 and isoform v5 are expressed in microvascular endothelial cells (at protein level).
Background: CDK5 regulatory subunit-associated protein 2 is a protein that in humans is encoded by the CDK5RAP2 gene. This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.
- 分子量
- 250 kDa
- 基因ID
- 55755
- 途径
- M Phase, SARS-CoV-2 Protein Interactome
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