CDK5RAP2 抗体 (Regulatory Subunit) (Biotin)
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Quick Overview for CDK5RAP2 抗体 (Regulatory Subunit) (Biotin) (ABIN7147231)
抗原
See all CDK5RAP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 996-1111, Regulatory Subunit
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原理
- CDK5RAP2 Antibody, Biotin conjugated
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human CDK5 regulatory subunit-associated protein 2 protein (996-1111AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))
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别名
- CDK5RAP2
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背景
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Background: Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regulation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Together with MAPRE1, it may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends. Regulates centrosomal maturation by recruitment of a gamma-tubulin ring complex onto centrosomes (PubMed:26485573).
Aliases: C48 antibody, CDK5 activator-binding protein C48 antibody, CDK5 regulatory subunit associated protein 2 antibody, CDK5 regulatory subunit-associated protein 2 antibody, CDK5RAP2 antibody, centrosomal protein 215 kDa antibody, Centrosome-associated protein 215 antibody, CEP215 antibody, CK5P2_HUMAN antibody, MCPH3 antibody
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UniProt
- Q96SN8
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途径
- M Phase, SARS-CoV-2 Protein Interactome
抗原
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