GANP 抗体 (AA 1275-1715)
Quick Overview for GANP 抗体 (AA 1275-1715) (ABIN7599898)
抗原
See all GANP (MCM3AP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1275-1715
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原理
- Anti-GANP/MCM3AP Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-GANP/MCM3AP Antibody Picoband® (ABIN7599898). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GANP/MCM3AP recombinant protein (Position: R1275-H1715). Human MCM3AP shares 80.9% amino acid (aa) sequence identity with mouse MCM3AP.
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亚型
- IgG
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anti-Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP) (C-Term) antibody
MCM3AP 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP) (AA 293-442) antibodyMCM3AP 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5B2C4 unconjugated
anti-Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP) (AA 292-435) antibodyMCM3AP 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP) (AA 1-100) antibodyMCM3AP 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1H3 unconjugated
anti-Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP) (AA 250-550) antibodyMCM3AP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP) (AA 1841-1890) antibodyMCM3AP 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP) (C-Term) antibodyMCM3AP 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP) (C-Term) antibodyMCM3AP 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Abe, E., Kuwahara, K., Yoshida, M., Suzuki, M., Terasaki, H., Matsuo, Y., Takahashi, E., Sakaguchi, N. Structure, expression, and chromosomal localization of the human gene encoding a germinal center-associated nuclear protein (GANP) that associates with MCM3 involved in the initiation of DNA replication. Gene 255: 219-227, 2000. 2. Karakaya, M., Mazaheri, N., Polat, I., Bharucha-Goebel, D., Donkervoort, S., Maroofian, R., Shariati, G., Hoelker, I., Monaghan, K., Winchester, S., Zori, R., Galehdari, H., Bonnemann, C. G., Yis, U., Wirth, B. Biallelic MCM3AP mutations cause Charcot-Marie-Tooth neuropathy with variable clinical presentation. (Letter) Brain 140: e65, 2017. Note: Electronic Article. 3. Kennerson, M. L., Corbett, A. C., Ellis, M., Perez-Siles, G., Nicholson, G. A. A novel MCM3AP mutation in a Lebanese family with recessive Charcot-Marie-Tooth neuropathy. (Letter) Brain 141: e66, 2018. Note: Electronic Article. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))
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别名
- MCM3AP
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: 80 kDa MCM3-associated protein is a protein that in humans is encoded by the MCM3AP gene. The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.
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分子量
- 218 kDa
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基因ID
- 8888
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UniProt
- O60318
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途径
- Protein targeting to Nucleus
抗原
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