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GANP 抗体 (C-Term)

MCM3AP 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261878
发货至: 中国
  • 抗原 See all GANP (MCM3AP) 抗体
    GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))
    抗原表位
    • 15
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    C-Term
    适用
    • 41
    • 13
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 39
    • 2
    克隆类型
    • 39
    • 2
    多克隆
    标记
    • 16
    • 3
    • 3
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    • 2
    • 2
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    • 1
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    This GANP antibody is un-conjugated
    应用范围
    • 28
    • 14
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    GANP Antibody detects endogenous levels of total GANP.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human GANP, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))
    别名
    MCM3AP (MCM3AP 产品)
    别名
    GANP antibody, MAP80 antibody, SAC3 antibody, mKIAA0572 antibody, minichromosome maintenance complex component 3 associated protein antibody, germinal-center associated nuclear protein antibody, Mcm3ap antibody, MCM3AP antibody, mcm3ap antibody, LOC100026233 antibody
    背景

    Description: Isoform GANP: Essential for the generation of high-affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation-dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells (By similarity). Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.

    Gene: MCM3AP

    分子量
    218kDa
    基因ID
    8888
    UniProt
    O60318
    途径
    Protein targeting to Nucleus
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