GANP 抗体 (AA 1841-1890)
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北京 101111
Quick Overview for GANP 抗体 (AA 1841-1890) (ABIN1533285)
抗原
See all GANP (MCM3AP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1841-1890
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原理
- GANP Antibody
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特异性
- GANP Polyclonal Antibody detects endogenous levels of GANP protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human GANP. AA range:1841-1890
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))
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别名
- GANP
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背景
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Synonyms: MCM3AP, GANP, KIAA0572, MAP80, 80 kDa MCM3-associated protein, Protein GANP
Background: The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication.The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability. [provided by RefSeq, Jan 2014],
Gene Name: MCM3AP
Protein Name: 80 kDa MCM3-associated protein
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分子量
- 218 kDa
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基因ID
- 8888
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OMIM
- 603294
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UniProt
- O60318
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途径
- Protein targeting to Nucleus
抗原
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