HPD 抗体 (AA 12-357)
Quick Overview for HPD 抗体 (AA 12-357) (ABIN7599818)
抗原
See all HPD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 12-357
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原理
- Anti-HPD Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-HPD Antibody Picoband® (ABIN7599818). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HPD recombinant protein (Position: E12-Q357).
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亚型
- IgG
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anti-4-Hydroxyphenylpyruvate Dioxygenase (HPD) (AA 2-393) antibody
HPD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-4-Hydroxyphenylpyruvate Dioxygenase (HPD) (AA 1-393) antibodyHPD 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-4-Hydroxyphenylpyruvate Dioxygenase (HPD) antibodyKO Validated HPD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-4-Hydroxyphenylpyruvate Dioxygenase (HPD) (AA 2-393) antibodyHPD 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-4-Hydroxyphenylpyruvate Dioxygenase (HPD) (AA 160-269) antibodyHPD 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F3 unconjugated
anti-4-Hydroxyphenylpyruvate Dioxygenase (HPD) (AA 92-121), (N-Term) antibodyHPD 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17892 unconjugated
anti-4-Hydroxyphenylpyruvate Dioxygenase (HPD) antibodyHPD 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-4-Hydroxyphenylpyruvate Dioxygenase (HPD) (C-Term) antibodyHPD 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-4-Hydroxyphenylpyruvate Dioxygenase (HPD) (AA 179-228) antibodyHPD 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-4-Hydroxyphenylpyruvate Dioxygenase (HPD) (AA 255-284), (C-Term) antibodyHPD 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB21004 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Awata, H., Endo, F., Matsuda, I. Structure of the human 4-hydroxyphenylpyruvic acid dioxygenase gene (HPD). Genomics 23: 534-539, 1994. 2. Borden, M., Holm, J., Leslie, J., Sweetman, L., Nyhan, W. L., Fleisher, L., Nadler, H., Lewis, D., Scott, C. R. Hawkinsinuria in two families. Am. J. Med. Genet. 44: 52-56, 1992. 3. Cerone, R., Holme, E., Schiaffino, M. C., Caruso, U., Maritano, L., Romano, C. Tyrosinemia type III: diagnosis and ten-year follow-up. Acta Paediat. 86: 1013-1015, 1997. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))
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别名
- HPD
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背景
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Synonyms: Elongator complex protein 3, Help3, ELP3
Tissue Specificity: Expressed at low levels in the more differentiated suprabasal regions of the small intestine, and at higher levels in the colon, mainly in the upper region and in scattered cells throughout the remaining epithelium. Also expressed in epithelial cells of bladder, ileum and stomach and at lower levels in pancreas and earskin. The phosphorylated form is nearly exclusively expressed in goblet cells of the small intestine and in the lumen-proximal cells of the colon (at protein level). Also expressed in jejunum and duodenum.
Background: The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 45 kDa
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基因ID
- 3242
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UniProt
- P32754
抗原
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