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HPD 抗体

KO Validated HPD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855744
发货至: 中国
  • 抗原 See all HPD 抗体
    HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))
    适用
    • 69
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    宿主
    • 75
    • 3
    克隆类型
    • 75
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    多克隆
    标记
    • 24
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    This HPD antibody is un-conjugated
    应用范围
    • 44
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    Western Blotting (WB)
    交叉反应
    产品特性
    Rabbit polyclonal antibody to HPD (4-hydroxyphenylpyruvate dioxygenase)
    HPD antibody [N1C2]
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human HPD. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product HPD Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: HepG2

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Shan, Lu, Li, Sheng, Fan, Qi, Liu, Zhang: "4-hydroxyphenylpyruvate dioxygenase promotes lung cancer growth via pentose phosphate pathway (PPP) flux mediated by LKB1-AMPK/HDAC10/G6PD axis." in: Cell death & disease, Vol. 10, Issue 7, pp. 525, (2020) (PubMed).

  • 抗原
    HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))
    别名
    4-hydroxyphenylpyruvate dioxygenase (HPD 产品)
    别名
    fb58f02 antibody, hpd antibody, wu:fb58f02 antibody, zgc:56326 antibody, zgc:92456 antibody, MGC146689 antibody, BA0240 antibody, PSPTO3553 antibody, DDBDRAFT_0203373 antibody, DDBDRAFT_0231603 antibody, DDBDRAFT_0231604 antibody, DDB_0203373 antibody, DDB_0231603 antibody, DDB_0231604 antibody, hppd antibody, 4-HPPD antibody, 4HPPD antibody, GLOD3 antibody, HPPDASE antibody, PPD antibody, 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE antibody, F12K11.9 antibody, F12K11_9 antibody, HPD antibody, P-HYDROXYPHENYLPYRUVATE DIOXYGENASE antibody, phytoene desaturation 1 antibody, Fla antibody, Flp antibody, Hppd antibody, Laf antibody, 4-hydroxyphenylpyruvate dioxygenase a antibody, 4-hydroxyphenylpyruvate dioxygenase antibody, 4-hydroxyphenylpyruvate dioxygenase b antibody, 4-hydroxyphenylpyruvate dioxygenase L homeolog antibody, 4-hydroxyphenylpyruvic acid dioxygenase antibody, hpda antibody, HPD antibody, hpdb antibody, hpd.L antibody, hpd antibody, BA_0240 antibody, hppD antibody, Hpd antibody, PDS1 antibody
    背景
    The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.

    分子量
    45 kDa
    基因ID
    3242
    UniProt
    P32754
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