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BCL3 抗体 (AA 118-420)

This anti-BCL3 antibody is a 兔 多克隆 antibody detecting BCL3 in WB, ELISA, IF, FACS 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7599795
发货至: 中国

Quick Overview for BCL3 抗体 (AA 118-420) (ABIN7599795)

抗原

See all BCL3 抗体
BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

适用

人, 小鼠, 大鼠

宿主

  • 46
  • 8
  • 5

克隆类型

  • 48
  • 11
多克隆

标记

  • 31
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BCL3 antibody is un-conjugated

应用范围

  • 45
  • 18
  • 13
  • 13
  • 12
  • 11
  • 10
  • 9
  • 7
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 118-420

    原理

    Anti-BCL3 Antibody Picoband®

    交叉反应 (详细)

    No cross reactivity with other proteins.

    产品特性

    Anti-BCL3 Antibody Picoband® (ABIN7599795). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PELI2 recombinant protein (Position: D118-D420). Human PELI2 shares 97.4% amino acid (aa) sequence identity with mouse?PELI2.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Bhatia, K., Huppi, K., McKeithan, T., Siwarski, D., Mushinski, J. F., Magrath, I. Mouse bcl-3: cDNA structure, mapping and stage-dependent expression in B lymphocytes. Oncogene 6: 1569-1573, 1991. 2. Carmody, R. J., Ruan, Q., Palmer, S., Hilliard, B., Chen, Y. H. Negative regulation of Toll-like receptor signaling by NF-kappa-B p50 ubiquitination blockade. Science 317: 675-678, 2007. 3. Franzoso, G., Bours, V., Park, S., Tomita-Yamaguchi, M., Kelly, K., Siebenlist, U. The candidate oncoprotein Bcl-3 is an antagonist of p50/NF-kappa-B-mediated inhibition. Nature 359: 339-342, 1992.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

    别名

    BCL3

    背景

    Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

    Tissue Specificity: Expressed in all tissues.

    Background: B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene. This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.

    分子量

    60 kDa

    基因ID

    602

    UniProt

    P20749

    途径

    NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
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