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BCL3 抗体 (AA 118-307)

This anti-BCL3 antibody is a 兔 多克隆 antibody detecting BCL3 in WB, ELISA 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7599792
发货至: 中国

Quick Overview for BCL3 抗体 (AA 118-307) (ABIN7599792)

抗原

See all BCL3 抗体
BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

适用

人, 小鼠, 大鼠

宿主

  • 46
  • 8
  • 5

克隆类型

  • 48
  • 11
多克隆

标记

  • 31
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BCL3 antibody is un-conjugated

应用范围

  • 45
  • 18
  • 13
  • 13
  • 12
  • 11
  • 11
  • 9
  • 8
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 118-307

    原理

    Anti-BCL3 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-BCL3 Antibody Picoband® (ABIN7599792). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human BCL3 recombinant protein (Position: E118-Y307).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Wulczyn FG, Naumann M, Scheidereit C (Sep 1992). "Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa B". Nature 358 (6387): 597-9. 2. Ohno H, Takimoto G, McKeithan TW (May 1990). "The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control". Cell 60 (6): 991-7. 3. McKeithan, T. W., Rowley, J. D., Shows, T. B., Diaz, M. O.Cloning of the chromosome translocation breakpoint junction of the t(14,19) in chronic lymphocytic leukemia.Proc. Nat. Acad. Sci. 84: 9257-9260, 1987.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

    别名

    BCL3

    背景

    Synonyms: CD3 antigen, epsilon polypeptide, CD3e molecule, Cd3e, Cd3e_predicted, rCG_58471

    Background: B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene. This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. The BCL3 gene is mapped to human chromosome 19. This protein functions as a transcriptional coactivator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.

    分子量

    60 kDa

    基因ID

    602

    UniProt

    P20749

    途径

    NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
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