BCL3 抗体 (AA 118-307)
Quick Overview for BCL3 抗体 (AA 118-307) (ABIN7599792)
抗原
See all BCL3 抗体适用
宿主
克隆类型
标记
应用范围
- 
    - 
                                            抗原表位
- AA 118-307
- 
                                            原理
- Anti-BCL3 Antibody Picoband®
- 
                                            交叉反应 (详细)
- No cross-reactivity with other proteins.
- 
                                            产品特性
- Anti-BCL3 Antibody Picoband® (ABIN7599792). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 
                                            纯化方法
- Immunogen affinity purified.
- 
                                            免疫原
- E.coli-derived human BCL3 recombinant protein (Position: E118-Y307).
- 
                                            亚型
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            应用备注
- 
                        Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
 Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
 ELISA, 0.1-0.5 μg/mL, -
 1. Wulczyn FG, Naumann M, Scheidereit C (Sep 1992). "Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa B". Nature 358 (6387): 597-9. 2. Ohno H, Takimoto G, McKeithan TW (May 1990). "The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control". Cell 60 (6): 991-7. 3. McKeithan, T. W., Rowley, J. D., Shows, T. B., Diaz, M. O.Cloning of the chromosome translocation breakpoint junction of the t(14,19) in chronic lymphocytic leukemia.Proc. Nat. Acad. Sci. 84: 9257-9260, 1987.
- 
                                            限制
- 仅限研究用
 
- 
                                            
- 
    - 
                                            状态
- Lyophilized
- 
                                            溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 
                                            浓度
- 500 μg/mL
- 
                                            缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
- 
                                            储存条件
- 4 °C,-20 °C
- 
                                            储存方法
- 
                        Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
 It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
 
- 
                                            
- 
    - BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
- 
                                            别名
- BCL3
- 
                                            背景
- 
                        Synonyms: CD3 antigen, epsilon polypeptide, CD3e molecule, Cd3e, Cd3e_predicted, rCG_58471 Background: B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene. This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. The BCL3 gene is mapped to human chromosome 19. This protein functions as a transcriptional coactivator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. 
- 
                                            分子量
- 60 kDa
- 
                                            基因ID
- 602
- 
                                            UniProt
- P20749
- 
                                            途径
- NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
 抗原
- 
                    
 
                                     
                                     
                                    