CRTC3 抗体 (AA 116-619)
Quick Overview for CRTC3 抗体 (AA 116-619) (ABIN7599779)
抗原
See all CRTC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 116-619
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原理
- Anti-CRTC3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CRTC3 Antibody Picoband® (ABIN7599779). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CRTC3 recombinant protein (Position: R116-L619).
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亚型
- IgG
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anti-CREB Regulated Transcription Coactivator 3 (CRTC3) antibody
CRTC3 适用: 人, 猴 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 5G9 unconjugated
anti-CREB Regulated Transcription Coactivator 3 (CRTC3) (AA 373-480) antibodyCRTC3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 3 (CRTC3) (AA 176-274) antibodyCRTC3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-CREB Regulated Transcription Coactivator 3 (CRTC3) (Internal Region) antibodyCRTC3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 3 (CRTC3) (AA 1-260) antibodyCRTC3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 3 (CRTC3) (AA 1-103) antibodyCRTC3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 3 (CRTC3) antibodyKD Validated CRTC3 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Monkey
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Iourgenko, V., Zhang, W., Mickanin, C., Daly, I., Jiang, C., Hexham, J. M., Orth, A. P., Miraglia, L., Meltzer, J., Garza, D., Chirn, G.-W., McWhinnie, E., and 9 others. Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells. Proc. Nat. Acad. Sci. 100: 12147-12152, 2003. 2. Song, Y., Altarejos, J., Goodarzi, M. O., Inoue, H., Guo, X., Berdeaux, R., Kim, J.-H., Goode, J., Igata, M., Paz, J. C., Hogan, M. F., Singh, P. K., and 12 others. CRTC3 links catecholamine signalling to energy balance. Nature 468: 933-939, 2010. 3. Wu, Z., Huang, X., Feng, Y., Handschin, C., Feng, Y., Gullicksen, P. S., Bare, O., Labow, M., Spiegelman, B., Stevenson, S. C. Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1-alpha transcription and mitochondrial biogenesis in muscle cells. Proc. Nat. Acad. Sci. 103: 14379-14384, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
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别名
- CRTC3
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背景
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Synonyms: Lymphotactin, C motif chemokine 1, Cytokine SCM-1, Lymphotaxin, Small-inducible cytokine C1, Xcl1, Lptn, Ltn, Scyc1
Tissue Specificity: Expressed in activated CD8 (+) T cells. In the thymus, expressed by medullary thymic epithelial cells.
Background: CREB-regulated transcription coactivator 3 is a protein that in humans is encoded by the CRTC3 gene. This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
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分子量
- 78 kDa
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基因ID
- 64784
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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