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CTLA4 抗体 (AA 110-223)

This 兔 多克隆 anti-CTLA4 antibody specifically detects CTLA4 in IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7599734
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for CTLA4 抗体 (AA 110-223) (ABIN7599734)

抗原

See all CTLA4 抗体
CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

适用

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宿主

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克隆类型

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多克隆

标记

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This CTLA4 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
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    AA 110-223

    原理

    Anti-CTLA4 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-CTLA4 Antibody (ABIN7599734). Tested in ELISA, IHC applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CTLA4 recombinant protein (Position: N110-N223).

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

    别名

    CTLA4

    背景

    Synonyms: Cytotoxic T-lymphocyte protein 4,Cytotoxic T-lymphocyte-associated antigen 4,CTLA-4,CD152,Ctla4,Cd152,

    Tissue Specificity: Widely expressed with highest levels in lymphoid tissues. .

    Background: CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein receptor that down regulates the immune system. It is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Blockade of CTLA4 expression in vitro augmented HIV-specific CD4-positive T-cell function.

    分子量

    25 kDa

    基因ID

    1493

    UniProt

    P16410

    途径

    Cancer Immune Checkpoints
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