PTH1R 抗体 (AA 102-446)
Quick Overview for PTH1R 抗体 (AA 102-446) (ABIN7599639)
抗原
See all PTH1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 102-446
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原理
- Anti-Parathyroid Hormone Receptor 1/PTH1R Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Parathyroid Hormone Receptor 1/PTH1R Antibody Picoband® (ABIN7599639). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Parathyroid Hormone Receptor 1/PTH1R recombinant protein (Position: R102-L446).
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亚型
- IgG
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anti-Parathyroid Hormone 1 Receptor (PTH1R) (pThr1) antibody
PTH1R 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) antibodyPTH1R 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4D2 unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 1268-1341) antibodyPTH1R 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 27-134) antibodyPTH1R 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 241-255), (Extracellular) antibodyPTH1R 适用: 大鼠 WB, IHC, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 485-593) antibodyPTH1R 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) antibodyPTH1R 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (N-Term) antibodyPTH1R 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 146-169) antibodyPTH1R 适用: 人, 小鼠, Cow, Pig, 犬, 猴, 马 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Parathyroid Hormone 1 Receptor (PTH1R) (AA 464-593) antibodyPTH1R 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Monkey
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bastepe, M., Raas-Rothschild, A., Silver, J., Weissman, I., Wientroub, S., Juppner, H., Gillis, D. A form of Jansen's metaphyseal chondrodysplasia with limited metabolic and skeletal abnormalities is caused by a novel activating parathyroid hormone (PTH)/PTH-related peptide receptor mutation. J. Clin. Endocr. Metab. 89: 3595-3600, 2004. 2. Decker, E., Stellzig-Eisenhauer, A., Fiebig, B. S., Rau, C., Kress, W., Saar, K., Ruschendorf, F., Hubner, N., Grimm, T., Weber, B. H. F. PTHR1 loss-of-function mutations in familial, nonsyndromic primary failure of tooth eruption. Am. J. Hum. Genet. 83: 781-786, 2008. 3. Hoogendam, J., Farih-Sips, H., Wynaendts, L. C., Lowik, C. W. G. M., Wit, J. M., Karperien, M. Novel mutations in the parathyroid hormone (PTH)/PTH-related peptide receptor type 1 causing Blomstrand osteochondrodysplasia types I and II. J. Clin. Endocr. Metab. 92: 1088-1095, 2007. 4. Wang, B., Yang, Y., Friedman, P. A. Na/H exchange regulatory factor 1, a novel AKT-associating protein, regulates extracellular signal-regulated kinase signaling through a B-Raf-mediated pathway. Mol. Biol. Cell 19: 1637-1645, 2008. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
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别名
- PTH1R
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背景
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Synonyms: Neutrophil cytosol factor 1, NCF-1, 47 kDa autosomal chronic granulomatous disease protein, 47 kDa neutrophil oxidase factor, NCF-47K, Neutrophil NADPH oxidase factor 1, Nox organizer 2, Nox-organizing protein 2, SH3 and PX domain-containing protein 1A, p47-phox, NCF1, NOXO2, SH3PXD1A
Tissue Specificity: Detected in peripheral blood monocytes and neutrophils (at protein level).
Background: Parathyroid hormone/parathyroid hormone-related peptide receptor, also known as PTH1R, PTHR, is a protein that in humans is encoded by the PTH1R gene. PTHR is a member of a family of G protein-coupled receptors. PTHR gene was mapped to the vicinity of the 3p21.3-p21.2 boundary by PCR analysis of human/rodent somatic cell hybrid panels using oligonucleotide primers designed to amplify a portion of the gene from genomic DNA. This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. PTH1R functions as a receptor for parathyroid hormone and for parathyroid hormone-related protein.
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分子量
- 66 kDa
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基因ID
- 5745
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UniProt
- Q03431
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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