MAML1 抗体 (AA 1-998)
Quick Overview for MAML1 抗体 (AA 1-998) (ABIN7599584)
抗原
See all MAML1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-998
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原理
- Anti-MAML1 Antibody Picoband®
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产品特性
- Anti-MAML1 Antibody Picoband® (ABIN7599584). Tested in WB, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MAML1 recombinant protein (Position: M1-K998). Human MAML1 shares 86.3% amino acid (aa) sequence identity with mouse MAML1.
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anti-Mastermind-Like 1 (MAML1) (N-Term) antibody
MAML1 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 1-45) antibodyMAML1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (N-Term) antibodyVerified MAML1 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 655-754) antibodyMAML1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 1-300) antibodyMAML1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 198-225) antibodyMAML1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB18757 unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 205-234), (Middle Region) antibodyMAML1 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Moellering, R. E., Cornejo, M., Davis, T. N., Del Bianco, C., Aster, J. C., Blacklow, S. C., Kung, A. L., Gilliland, D. G., Verdine, G. L., Bradner, J. E. Direct inhibition of the NOTCH transcription factor complex. Nature 462: 182-188, 2009. Note: Erratum: Nature 463: 384 only, 2010. 2. Nagase, T., Seki, N., Ishikawa, K., Tanaka, A., Nomura, N. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res. 3: 17-24, 1996. 3. Shen, H., McElhinny, A. S., Cao, Y., Gao, P., Liu, J., Bronson, R., Griffin, J. D., Wu, L. The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis. Genes Dev. 20: 675-688, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MAML1 (Mastermind-Like 1 (MAML1))
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别名
- MAML1
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背景
- Mastermind-like protein 1 is a protein that in humans is encoded by the MAML1 gene. This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.
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分子量
- 130 kDa
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基因ID
- 9794
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UniProt
- Q92585
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途径
- Notch Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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