Axin 抗体 (AA 1-811)
Quick Overview for Axin 抗体 (AA 1-811) (ABIN7599556)
抗原
See all Axin (AXIN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-811
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原理
- Anti-AXIN1 Antibody Picoband®
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产品特性
- Anti-AXIN1 Antibody Picoband® (ABIN7599556). Tested in WB, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human AXIN1 recombinant protein (Position: M1-K811). Human AXIN1 shares 86.2% and 82.8% amino acid (aa) sequence identity with mouse and rat AXIN1, respectively.
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anti-Axin 1 (AXIN1) (AA 546-752) antibody
AXIN1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4E9F1 unconjugated
anti-Axin 1 (AXIN1) (AA 618-827) antibodyAXIN1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 643-740) antibodyAXIN1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Axin 1 (AXIN1) (AA 546-752) antibodyAXIN1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4F10G1 unconjugated
anti-Axin 1 (AXIN1) (AA 653-862) antibodyAXIN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 710-738) antibodyAXIN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 761-862) antibodyAXIN1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 418-707) antibodyAXIN1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 654-863) antibodyAXIN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Axin 1 (AXIN1) (C-Term) antibodyVerified AXIN1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chen, H.-J., Lin, C.-M., Lin, C.-S., Perez-Olle, R., Leung, C. L., Liem, R. K. H. The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway. Genes Dev. 20: 1933-1945, 2006. 2. Goto, T., Matsuzawa, J., Iemura, S., Natsume, T., Shibuya, H. WDR26 is a new partner of Axin1 in the canonical Wnt signaling pathway. FEBS Lett. 590: 1291-1303, 2016. 3. Huang, S.-M. A., Mishina, Y. M., Liu, S., Cheung, A., Stegmeier, F., Michaud, G. A., Charlat, O., Wiellette, E., Zhang, Y., Wiessner, S., Hild, M., Shi, X., and 24 others. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature 461: 614-620, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Axin (AXIN1) (Axin 1 (AXIN1))
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别名
- AXIN1
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背景
- Axin-1 is a protein that in humans is encoded by the AXIN1 gene. This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants.
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分子量
- 110 kDa
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基因ID
- 8312
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UniProt
- O15169
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途径
- WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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