NBR1 抗体 (AA 1-665)
Quick Overview for NBR1 抗体 (AA 1-665) (ABIN7599518)
抗原
See all NBR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-665
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原理
- Anti-NBR1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-NBR1 Antibody Picoband® (ABIN7599518). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NBR1 recombinant protein (Position: M1-H665).
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亚型
- IgG
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anti-Neighbor of BRCA1 Gene 1 (NBR1) antibody
NBR1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) (AA 2-96) antibodyNBR1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 5C3 unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) (AA 2-96) antibodyNBR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6B11 unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) antibodyNBR1 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 小鼠 Monoclonal 4C6 unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) (AA 2-96) antibodyNBR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) (AA 1-966) antibodyNBR1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) antibodyNBR1 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) antibodyNBR1 适用: 人, 小鼠, 大鼠, 猴 IHC 宿主: 兔 Polyclonal unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) (AA 1-280) antibodyNBR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neighbor of BRCA1 Gene 1 (NBR1) (AA 776-825) antibodyNBR1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Monkey
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Brown, M. A., Nicolai, H., Xu, C.-F., Griffiths, B. L., Jones, K. A., Solomon, E., Hosking, L., Trowsdale, J., Black, D. M., McFarlane, R. Regulation of BRCA1. (Letter) Nature 372: 733 only, 1994. 2. Brown, M. A., Xu, C.-F., Nicolai, H., Griffiths, B., Chambers, J. A., Black, D., Solomon, E. The 5-prime end of the BRCA1 gene lies within a duplicated region of human chromosome 17q21. Oncogene 12: 2507-2513, 1996. 3. Campbell, I. G., Nicolai, H. M., Foulkes, W. D., Senger, G., Stamp, G. W., Allan, G., Boyer, C., Jones, K., Bast, R. C., Jr., Solomon, E., Trowsdale, J., Black, D. M. A novel gene encoding a B-box protein within the BRCA1 region at 17q21.1. Hum. Molec. Genet. 3: 589-594, 1994. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
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别名
- NBR1
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背景
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Synonyms: Segment polarity protein dishevelled homolog DVL-1,Dishevelled-1,DSH homolog 1,DVL1,
Tissue Specificity: Found in embryos and in adult liver and heart.
Background: Neighbor of BRCA1 gene 1 protein is a protein that in humans is encoded by the NBR1 gene. The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.
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分子量
- 140 kDa
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基因ID
- 4077
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UniProt
- Q14596
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途径
- Autophagy
抗原
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