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ATG4C 抗体 (AA 1-457)

This anti-ATG4C antibody is a 兔 多克隆 antibody detecting ATG4C in WB, ELISA, IF, ICC 和 FACS. Suitable for 人.
产品编号 ABIN7599415
发货至: 中国

Quick Overview for ATG4C 抗体 (AA 1-457) (ABIN7599415)

抗原

See all ATG4C 抗体
ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

适用

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宿主

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克隆类型

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多克隆

标记

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This ATG4C antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-457

    原理

    Anti-ATG4C Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-ATG4C Antibody Picoband® (ABIN7599415). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ATG4C recombinant protein (Position: M1-L457).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Agrotis, A., Pengo, N., Burden, J. J., Ketteler, R. Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells. Autophagy 15: 976-997, 2019. 2. Gross, M. B. Personal Communication. Baltimore, Md. 12/16/2020. 3. Li, M., Hou, Y., Wang, J., Chen, X., Shao, Z.-M., Yin, X.-M. Kinetics comparisons of mammalian Atg4 homologues indicates selective preferences toward diverse Atg8 substrates. J. Biol. Chem. 286: 7327-7338, 2011.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

    别名

    ATG4C

    背景

    Synonyms: Cationic amino acid transporter 3,CAT-3,CAT3,Cationic amino acid transporter y+,Solute carrier family 7 member 3,SLC7A3,ATRC3, CAT3,

    Tissue Specificity: Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala. .

    Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.

    分子量

    52 kDa

    基因ID

    84938

    途径

    Autophagy
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