MAPT 抗体 (AA 1-322)
Quick Overview for MAPT 抗体 (AA 1-322) (ABIN7599268)
抗原
See all MAPT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-322
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原理
- Anti-Tau/MAPT Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Tau/MAPT Antibody Picoband® (ABIN7599268). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Tau/MAPT recombinant protein (Position: M1-L322).
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亚型
- IgG
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anti-Microtubule-Associated Protein tau (MAPT) (pThr212) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer262) antibodyMAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer235) antibodyMAPT 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (AA 130-386) antibodyMAPT 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (AA 34-368) antibodyMAPT 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pThr181) antibodyMAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pThr205) antibodyMAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer404) antibodyMAPT 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer422) antibodyMAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer356) antibodyMAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Andreadis, A., Brown, W. M., Kosik, K. S.Structure and novel exons of the human tau gene.Biochemistry 31: 10626-10633, 1992. 2. Donlon, T. A., Harris, P., Neve, R. L.Localization of microtubule-associated protein tau (MTBT1) to chromosome 17q21. (Abstract)Cytogenet. Cell Genet. 46: 607, 1987. 3. Rademakers, R., Cruts, M., van Broeckhoven, C.The role of tau (MAPT) in frontotemporal dementia and related tauopathies.Hum. Mutat. 24: 277-295, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MAPT (Microtubule-Associated Protein tau (MAPT))
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别名
- MAPT
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背景
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Synonyms: Platelet-derived growth factor receptor beta, PDGF-R-beta, PDGFR-beta, Beta platelet-derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, Platelet-derived growth factor receptor 1, PDGFR-1, CD140b, PDGFRB, PDGFR, PDGFR1
Background: MAPT, Microtubule-associated protein tau, appears to be enriched in axons. The MAPT gene is assigned to chromosome 17 by hybridization of a cDNA clone to flow-sorted and spot-blotted chromosomes and to 17q21 by in situ hybridization, containing 16 exons. The tau proteins are the product of alternative splicingfrom a single gene that in humans is designated MAPT. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons in the central nervous system and are less common elsewhere. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease.
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分子量
- 50-70 kDa
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基因ID
- 4137
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UniProt
- P10636
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途径
- MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
抗原
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