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MAPT 抗体 (pSer404)

Name: MAPT 抗体 (pSer404)
Brand: antibodies-online
SKU: ABIN7138604
Availability: OutOfStock

MAPT 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts from C6 cells, treated with calf intestinal phosphatase (CIP), using Tau (Phospho-Ser404) Antibody. (MAPT 抗体 (pSer404))

Immunofluorescence staining of methanol-fixed Hela cells using Tau(Phospho-Ser404) Antibody. (MAPT 抗体 (pSer404))

Immunohistochemical analysis of paraffin-embedded rat hippocampal region tissue from a model with Alzheimer (MAPT 抗体 (pSer404))

IHC

Western blot analysis of extracts from C6 cells using Tau(Phospho-Ser404) Antibody. (MAPT 抗体 (pSer404))

4 images

产品编号 ABIN7138604

发货至: 中国

Datasheet as PDF

抗原 See all MAPT 抗体

MAPT (Microtubule-Associated Protein tau (MAPT))
抗原表位
11

9

9

8

7

6

6

6

6

6

6

5

5

5

5

4

4

4

4

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
pSer404
适用
213

110

100

15

12

8

7

6

4

3

2

2

2

1

1

1
人
宿主
200

18

6
兔
Compatible Secondaries
克隆类型
194

30
多克隆
标记
178

17

6

5

2

2

2

2

2

2

2

2

1

1
This MAPT antibody is un-conjugated
应用范围
194

118

60

35

25

21

14

3

2

2

2

2

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

交叉反应

人, 小鼠, 大鼠

纯化方法

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

免疫原

Peptide sequence around phosphorylation site of serine 404 (D-T-S(p)-P-R) derived from Human Tau.

亚型

IgG

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anti-Microtubule-Associated Protein tau (MAPT) (AA 1-100) antibody
MAPT 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pThr205) antibody
MAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pThr181) antibody
MAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer404) antibody
MAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer396) antibody
MAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer422) antibody
MAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer356) antibody
MAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,

限制

仅限研究用
状态

Liquid

缓冲液

Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
抗原

MAPT (Microtubule-Associated Protein tau (MAPT))

别名

MAPT (MAPT 产品)

别名

DDPAC antibody, FTDP-17 antibody, MAPTL antibody, MSTD antibody, MTBT1 antibody, MTBT2 antibody, PPND antibody, TAU antibody, AI413597 antibody, AW045860 antibody, Mtapt antibody, Tau antibody, RNPTAU antibody, pTau antibody, tau antibody, xtp antibody, MAPT antibody, PHF-tau antibody, slc6a6 antibody, taut antibody, wu:fc26e12 antibody, microtubule associated protein tau antibody, microtubule-associated protein tau antibody, microtubule associated protein tau S homeolog antibody, Microtubule-associated protein tau antibody, solute carrier family 6 (neurotransmitter transporter), member 6b antibody, MAPT antibody, Mapt antibody, mapt.S antibody, LOC5580230 antibody, CpipJ_CPIJ013260 antibody, tau antibody, slc6a6b antibody

背景

Background:
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Li G, Yin H, et.al .(2004) J Biol Chem , 279(16): 15938-45.
Noble W, et al. (2003) Neuron , 38(4): 555-65.
Giasson BI, et al.(2002). Biochemistry, 41(51): 15376-87.
Lee G., et.al. (1989). Neuron 2:1615-1624.
Andreadis A.et.al. (1992) Biochemistry 31:10626-10633.
Aliases: AI413597 antibody, AW045860 antibody, DDPAC antibody, FLJ31424 antibody, FTDP 17 antibody, G protein beta1/gamma2 subunit interacting factor 1 antibody, MAPT antibody, MAPTL antibody, MGC134287 antibody, MGC138549 antibody, MGC156663 antibody, Microtubule associated protein tau antibody, Microtubule associated protein tau isoform 4 antibody, Microtubule-associated protein tau antibody, MSTD antibody, Mtapt antibody, MTBT1 antibody, MTBT2 antibody, Neurofibrillary tangle protein antibody, Paired helical filament tau antibody, Paired helical filament-tau antibody, PHF tau antibody, PHF-tau antibody, PPND antibody, PPP1R103 antibody, Protein phosphatase 1, regulatory subunit 103 antibody, pTau antibody, RNPTAU antibody, TAU antibody, TAU_HUMAN antibody, Tauopathy and respiratory failure antibody, Tauopathy and respiratory failure, included antibody

UniProt

P10636

途径

MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size