UBD 抗体 (AA 1-163)
Quick Overview for UBD 抗体 (AA 1-163) (ABIN7599019)
抗原
See all UBD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-163
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原理
- Anti-FAT10/UBD Picoband® Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-FAT10/UBD Picoband® Antibody (ABIN7599019). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FAT10/UBD recombinant protein (Position: M1-I163).
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亚型
- IgG
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anti-Ubiquitin D (UBD) (AA 1-155) antibody
UBD 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin D (UBD) (AA 120-153) antibodyUBD 适用: 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin D (UBD) (AA 1-165) antibodyUBD 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin D (UBD) (Internal Region) antibodyUBD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin D (UBD) antibodyUBD 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin D (UBD) (AA 1-165) antibodyUBD 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin D (UBD) (AA 1-165) antibodyUBD 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin D (UBD) (AA 1-165) antibodyUBD 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7D8 unconjugated
anti-Ubiquitin D (UBD) (AA 1-165) antibodyUBD 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin D (UBD) (AA 27-40), (N-Term) antibodyUBD 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bates, E. E. M., Ravel, O., Dieu, M.-C., Ho, S., Guret, C., Bridon, J.-M., Ait-Yahia, S., Briere, F., Caux, C., Banchereau, J., Lebecque, S. Identification and analysis of a novel member of the ubiquitin family expressed in dendritic cells and mature B cells. Europ. J. Immun. 27: 2471-2477, 1997. 2. Buchsbaum, S., Bercovich, B., Ciechanover, A. FAT10 is a proteasomal degradation signal that is itself regulated by ubiquitination. Molec. Biol. Cell 23: 225-232, 2012. 3. Chiu, Y.-H., Sun, Q., Chen, Z. J. E1-L2 activates both ubiquitin and FAT10. Molec. Cell 27: 1014-1023, 2007. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- UBD (Ubiquitin D (UBD))
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别名
- UBD
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背景
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Synonyms: Ubiquitin D, Diubiquitin, Ubiquitin-like protein FAT10, UBD, FAT10
Tissue Specificity: Preferentially expressed in activated T lymphocytes.
Background: Ubiquitin D is a protein that in humans is encoded by the UBD gene. It is mapped to 6p22.1. This gene encodes a protein which contains two ubiquitin-like domains and appears to have similar function to ubiquitin. Through covalent attachment, the encoded protein targets other proteins for 26S proteasome degradation. This protein has been implicated to function in many cellular processes, including caspase-dependent apoptosis, formation of aggresomes, mitotic regulation, and dendritic cell maturation. Upregulation of this gene may promote inflammation in chronic kidney disease and has been observed in many cancer types.
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分子量
- 18 kDa
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基因ID
- 10537
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UniProt
- O15205
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途径
- Ubiquitin Proteasome Pathway
抗原
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