UBD 抗体 (AA 120-153)
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- 抗原 See all UBD 抗体
- UBD (Ubiquitin D (UBD))
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抗原表位
- AA 120-153
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBD antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Antigen affinity purified
- 免疫原
- A portion of amino acids 120-153 from the human protein was used as the immunogen for this FAT10 antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product UBD Primary Antibody
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anti-Ubiquitin D (UBD) (AA 1-155) antibody
UBD 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin D (UBD) antibodyUBD 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Ubiquitin D (UBD) (AA 1-165) antibodyUBD 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin D (UBD) (Internal Region) antibodyUBD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin D (UBD) antibodyUBD 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin D (UBD) (AA 1-165) antibodyUBD 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin D (UBD) (AA 1-165) antibodyUBD 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin D (UBD) (AA 1-165) antibodyUBD 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7D8 unconjugated
anti-Ubiquitin D (UBD) (AA 1-165) antibodyUBD 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin D (UBD) (AA 27-40), (N-Term) antibodyUBD 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Titration of the FAT10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the FAT10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- UBD (Ubiquitin D (UBD))
- 别名
- FAT10 (UBD 产品)
- 别名
- FAT10 antibody, GABBR1 antibody, UBD-3 antibody, ubiquitin D antibody, UBD antibody, Ubd antibody
- 背景
- FAT10/UBD is a Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome, in a NUB1L-dependent manner. Probably functions as a survival factor. Conjugation ability activated by UBA6. Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2). Regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha. Required for TNF-alpha-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs). May be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses. Mediates mitotic non-disjunction and chromosome instability, in long-term in vitro culture and cancers, by abbreviating mitotic phase and impairing the kinetochore localization of MAD2L1 during the prometaphase stage of the cell cycle. May be involved in the formation of aggresomes when proteasome is saturated or impaired. Mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN). [UniProt]
- UniProt
- O15205
- 途径
- Ubiquitin Proteasome Pathway
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