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CTLA4 抗体 (AA 36-161)

This anti-CTLA4 antibody is a 小鼠 单克隆 antibody detecting CTLA4 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7596075
发货至: 中国

Quick Overview for CTLA4 抗体 (AA 36-161) (ABIN7596075)

抗原

See all CTLA4 抗体
CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CTLA4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

AT4C8
  • 抗原表位

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    AA 36-161

    原理

    Human CTLA4 antibody

    纯化方法

    protein-A affinity chromatography

    免疫原

    Recombinant human CTLA4 (36-161aa) purified from E. coli

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

    别名

    CTLA4

    背景

    CTLA4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein receptor that downregulates the immune system. CTLA4 is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Mutations in CTLA4 have been associated with insulin-dependent diabetes mellitus, Graves' disease, Hashimoto's thyroiditis, celiac disease and other autoimmune diseases.

    NCBI登录号

    NP_005205

    途径

    Cancer Immune Checkpoints
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