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PINK1 抗体 (AA 112-496) (FL490)

This anti-PINK1 antibody is a 小鼠 单克隆 antibody detecting PINK1 in IHC 和 ICC. Suitable for 人.
产品编号 ABIN7595423
发货至: 中国

Quick Overview for PINK1 抗体 (AA 112-496) (FL490) (ABIN7595423)

抗原

See all PINK1 抗体
PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

适用

  • 89
  • 29
  • 10
  • 2
  • 2
  • 1
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  • 1

宿主

  • 58
  • 43
  • 1
小鼠

克隆类型

  • 62
  • 42
单克隆

标记

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  • 1
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This PINK1 antibody is conjugated to FL490

应用范围

  • 78
  • 61
  • 44
  • 27
  • 20
  • 8
  • 6
  • 6
  • 5
  • 3
  • 1
  • 1
Immunohistochemistry (IHC), Immunocytochemistry (ICC)

克隆位点

N4-15
  • 抗原表位

    • 27
    • 8
    • 7
    • 6
    • 6
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    • 3
    • 2
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    • 1
    AA 112-496

    原理

    Anti-Pink1 PTEN Induced Putative Kinase 1 Antibody FL490 Conjugate

    特异性

    No off-targets reported

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Description: Our Anti-Pink1 PTEN induced putative kinase 1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N4/15. It detects human, mouse, and rat Pink1 PTEN induced putative kinase 1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

    Manufacturer Comment: We produce our Pink1 PTEN induced putative kinase 1 mouse monoclonal primary antibody from hybridoma clone N4/15. It is great in IHC, ICC and is purified by Protein A chromatography.

    纯化方法

    Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

    纯度

    > 90 % specific antibody

    免疫原

    Fusion protein amino acids 112-496 of human Pink1 (accession number NP_115785) produced recombinantly in E. Coli

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.09 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

    有效期

    12 months
  • 抗原

    PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

    别名

    Pink1 PTEN induced putative kinase 1

    背景

    Synonyms: Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)

    Target Description: PTEN Induced Kinase 1 is encoded by the gene PINK1. PINK1 is a member of the protein kinase superfamily, Ser/Thr protein kinase family. PINK1 is a serine/threonine protein kinase that protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. PINK1 is highly expressed in the heart, skeletal muscle, and testis. Diseases associated with PINK1 include Parkinson Disease 6, Autosomal Recessive Early-Onset and Parkinson Disease 2, Autosomal Recessive Juvenile.

    Gene Name Alternatives: PINK1

    分子量

    63 kDa

    途径

    Autophagy
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