Beclin 1 抗体
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北京 101111
Quick Overview for Beclin 1 抗体 (ABIN7595319)
抗原
See all Beclin 1 (BECN1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Chicken antibody to Beclin-1
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特异性
- Specific for Beclin-1.
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交叉反应
- 人, Marmoset, 小鼠, 大鼠
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交叉反应 (详细)
- Other species not yet tested.
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纯化方法
- Purified IgY
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免疫原
- Truncated recombinant mouse Beclin-1 conjugated to blue carrier protein has been used as the antigen. The antigen shares 99% identity with human and rat sequences.
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亚型
- IgY
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应用备注
- IHC WB. Use at a dilution of 1 : 1000. The optimal dilution should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term.
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有效期
- 12 months
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- Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
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别名
- Beclin-1
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背景
- Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation metamorphosis non-apoptotic cell death and aging. Reduced levels of autophagy have been described in some malignant tumors and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. It may play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus. May play a role in autophagy. SUBCELLULAR LOCATION: Cytoplasm. Golgi apparatus membrane, Peripheral membrane protein. Note: Expressed in dendrites and cell bodies of cerebellar Purkinje cells TISSUE SPECIFICITY: Ubiquitous
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途径
- Autophagy
抗原
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