Apelin Receptor 抗体 (Extracellular, N-Term)
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Quick Overview for Apelin Receptor 抗体 (Extracellular, N-Term) (ABIN7581824)
抗原
See all Apelin Receptor (APLNR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-17, Extracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to Apelin Receptor
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序列
- DGYNYYGADN QSEC
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预测反应
- Mouse,human - identical
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产品特性
- Anti-Apelin/APJ Receptor (extracellular) Antibody (ABIN7581824) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, live cell flow cytometry, and immunohistochemistry applications. It has been designed to recognize Apelin receptor from mouse, rat, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- DGYNYYGADNQSEC, corresponding to amino acid residues 4-17 of rat apelin receptor
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亚型
- IgG
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anti-Apelin Receptor (APLNR) (AA 52-66) antibody
APLNR 适用: 人, 大鼠, 小鼠 WB, IF (p), IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Apelin Receptor (APLNR) (AA 309-380) antibodyAPLNR 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apelin Receptor (APLNR) (C-Term) antibodyAPLNR 适用: 人, 小鼠, 兔, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Apelin Receptor (APLNR) (Extracellular Domain) antibodyAPLNR 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Apelin Receptor (APLNR) (N-Term) antibodyAPLNR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Apelin Receptor (APLNR) (AA 310-380) antibodyAPLNR 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Apelin Receptor (APLNR) antibodyAPLNR 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Apelin Receptor (APLNR) (Cytoplasmic Domain) antibodyAPLNR 适用: 人, 马, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Apelin Receptor (APLNR) (Cytoplasmic Domain) antibodyAPLNR 适用: 人, 小鼠 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Apelin Receptor (APLNR) (AA 46-95) antibodyAPLNR 适用: 人, 马, 豚鼠, Hamster, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: 2.5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: 1:600
IP: The optimal concentration should be determined by the user
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- Apelin Receptor (APLNR)
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别名
- APLNR
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背景
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Synonyms: APLNR, Angiotensin receptor-like 1, AGTRL1, G-protein coupled receptor APJ, GPCR34
Description: The apelin receptor (APJ) is a member of the G-protein coupled receptor gene family, encoded by the APLNR gene. The apelin receptor and its endogenous ligand, apelin, have been suggested to act as key mediators of physiological responses to multiple homeostatic actions, including cardiovascular control, water balance, hypothalamic-pituitary-adrenal (HPA) axis regulation and metabolic homeostasis.Apelin receptor structure contains seven hydrophobic transmembrane domains, with several sites for phosphorylation by protein kinase A, and sites for palmitoylation and glycosylation. The N-terminal glycosylation is implicated in the receptor's expression, stability, correct folding of the protein and ligand binding. The C-terminal palmitoylation has been reported to play a role in membrane association. These modifications can influence the internalization, dimerization and ligand binding of the receptor. Human apelin receptor shares 92 % homology with mouse receptor and 90 % homology with rat receptor.Apelin expression can be detected in several brain regions including the human caudate nucleus, corpus callosum, hippocampus, substantia nigra, subthalamic nucleus, medulla and spinal cord. Apelin receptor is also expressed in the spleen, placenta and cardiovascular tissues and small amounts in the small intestine, lung, stomach, colonic mucosa and ovary.
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基因ID
- 83518
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UniProt
- Q9JHG3
抗原
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