SLAMF1 抗体 (Elab Fluor®700)
Quick Overview for SLAMF1 抗体 (Elab Fluor®700) (ABIN7566905)
抗原
See all SLAMF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Elab Fluor®700 Anti-Mouse CD150/SLAM Antibody[TC15-12F12.2]
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亚型
- IgG2a, kappa
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应用备注
- Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
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说明
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Matching Isotype Control: E-AB-F09742M1
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
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储存条件
- 4 °C
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储存方法
- This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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有效期
- 12 months
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- SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
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别名
- CD150/SLAM
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背景
- CD 150,Signaling lymphocytic activation molecule,Slam,Slamf1,CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.
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基因ID
- 27218
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UniProt
- Q9QUM4
抗原
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