ERK1/2 抗体 (AA 301-358) (Biotin)
Quick Overview for ERK1/2 抗体 (AA 301-358) (Biotin) (ABIN723727)
抗原
See all ERK1/2 (MAPK1/3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-358
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交叉反应
- 人, 小鼠, Pig, 大鼠
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预测反应
- Dog,Cow,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from mouse ERK2
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (AA 301-358) antibody
MAPK1/3 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC (p), IF (cc), FACS, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) antibodyMAPK1/3 适用: 人, 小鼠, 大鼠, Cow, Pig, 斑马鱼, 犬, 绵羊, 猴, 鱼, 马 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (pThr202), (pTyr204) antibodyMAPK1/3 适用: 人, 小鼠, 大鼠, Cow WB, ELISA, IHC (p), IF (cc), FACS, IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (pThr183), (pTyr185) antibodyMAPK1/3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (pThr185), (pThr202) antibodyMAPK1/3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (C-Term) antibodyMAPK1/3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) antibodyMAPK1/3 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 3F8 unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (pThr183), (pTyr185) antibodyMAPK1/3 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), IF (cc), FACS, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (pThr202), (pTyr204) antibodyMAPK1/3 适用: 人, 小鼠 WB, ELISA, DB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 1/3 (MAPK1/3) (pTyr205), (pTyr222) antibodyMAPK1/3 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 小鼠 Monoclonal 4D4 unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
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别名
- ERK1 + ERK2
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背景
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Synonyms: Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, Mapk1, Erk2, Mapk, Prkm1
Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have already been discovered for ERKs. Many of these substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation. However, other substrates are found in the cytosol as well as in other cellular organelles, and those are responsible for processes such as translation, mitosis and apoptosis. Moreover, the MAPK/ERK cascade is also involved in the regulation of the endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC), as well as in the fragmentation of the Golgi apparatus during mitosis.
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基因ID
- 26413
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UniProt
- P63085
抗原
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