Recombinant LAG3 抗体
Quick Overview for Recombinant LAG3 抗体 (ABIN7543410)
抗原
See all LAG3 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-LAG-3 [22G3], Rabbit IgG, kappa
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特异性
- The antibody is specific for LAG3. Lymphocyte activation gene 3 protein is an inhibitory receptor on antigen activated T-cells. It delivers inhibitory signals upon binding to ligands, such as FGL1.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing mice with recombinant LAG3 protein.
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亚型
- IgG kappa
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应用备注
- The antibody specifically detected LAG3 protein in Western blot analysis. The antibody and the commercial antibody EPR20261 were used to stain tonsillar granulocytes and granulocytes in the appendix. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 22G3 was higher than the commercial antibody. The antibody and the commercially available antibody E3 were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN113234159A).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
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别名
- LAG-3
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背景
- CD223, LAG3, Lymphocyte-activation gene-3, Lymphocyte activation gene 3 protein, LAG-3, CGMCNO 20774
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UniProt
- P18627
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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