Recombinant FcRn 抗体
Quick Overview for Recombinant FcRn 抗体 (ABIN7543363)
抗原
See all FcRn 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-FcRn [h22-0015], Mouse IgG1, kappa
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特异性
- The antibody is specific for human FcRn. The neonatal Fc receptor is a cell surface receptor that transfers passive humoral immunity from the mother to the newborn.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing Balb/c mice with recombinant FcRn.
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亚型
- IgG1 kappa
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anti-neonatal Fc Receptor (FcRn) antibody
FcRn 适用: 人 ELISA, IF, FACS, cELISA, Func 宿主: 小鼠 Monoclonal ADM31 unconjugated
anti-neonatal Fc Receptor (FcRn) antibodyFcRn 适用: 人 ELISA, IF, FACS, cELISA 宿主: 小鼠 Monoclonal DVN24 unconjugated
anti-neonatal Fc Receptor (FcRn) (AA 24-297) antibodyFcRn 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-neonatal Fc Receptor (FcRn) (AA 24-365) antibodyFcRn 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-neonatal Fc Receptor (FcRn) (AA 24-215) antibodyFcRn 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FCGRT-2932 unconjugated
anti-neonatal Fc Receptor (FcRn) (AA 24-297) antibodyFcRn 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5F3D1 unconjugated
anti-neonatal Fc Receptor (FcRn) (AA 24-297) antibodyFcRn 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2B3B11 unconjugated
anti-neonatal Fc Receptor (FcRn) (AA 25-300) antibodyFcRn 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-neonatal Fc Receptor (FcRn) (N-Term) antibodyFcRn 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-neonatal Fc Receptor (FcRn) (N-Term) antibodyFcRn 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- The antibody was employed in blocking experiments with HEK293 cells that overexpress FcRn. The results showed that the antibody has a good effect of blocking the binding of IgG to FcRn at the cellular level (IC50: 11.4nM). The effect of the antibody was tested in human FcRn transgenic mice. The antibody was able to increase IgG catabolism in vivo by blocking FcRn binding (CN113484526).
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- FcRn (neonatal Fc Receptor (FcRn))
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别名
- FcRn
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背景
- IgG receptor FcRn large subunit p51, FCGRT, IgG Fc fragment receptor transporter alpha chain, Neonatal Fc receptor
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UniProt
- P55899
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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