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Recombinant CD3 epsilon 抗体 (AA 23-126)

This anti-CD3 epsilon antibody is a 小鼠 单克隆 antibody detecting CD3 epsilon in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7543303
发货至: 中国

Quick Overview for Recombinant CD3 epsilon 抗体 (AA 23-126) (ABIN7543303)

抗原

See all CD3 epsilon (CD3E) 抗体
CD3 epsilon (CD3E)

抗体类型

Recombinant Antibody

适用

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小鼠

克隆类型

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单克隆

标记

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This CD3 epsilon antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

33H1
  • 抗原表位

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    AA 23-126

    原理

    Anti-CD3e [33H1], Mouse IgG2a, kappa

    特异性

    This antibody binds human CD3e. It is part of TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. It also plays a role in signal transduction during T cell development and in correct T-cell development.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2a

    纯化方法

    Protein A affinity purified

    免疫原

    The original antibody was generated by immunizing BALB/c mice with recombinant human CD3 antigen (amino acids 23-126).

    亚型

    IgG2a kappa
  • 应用备注

    This binding specificity of this antibody for human CD3e was checked using ELISA. The affinity constant of the original IgG2a antibody was determined to be 1.92x10^9 M^(-1). This antibody can recognize human CD3e recombinant protein in an immunoblot assay. This antibody is similar to commercially available anti-CD3 antibody SP7 in immunohistochemical staining of T cell lymphomas. This antibody can also be used for the immunohistochemical staining of normal tissues like brain, heart, cerebellum, esophageal, adrenal, stomach, ovary, small intestine, pancreatic, colorectal, paratony gland, liver, pituitary, salivary gland, testicular, kidney, thyroid, prostate, breast, uterus, spleen , Bladder, tonsil, skeletal muscle, thymus (young children), skin, bone marrow, peripheral nerve, lung and melodder cells (CN111363043).

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD3 epsilon (CD3E)

    别名

    CD3e

    背景

    T3E, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3-ε, CGMCC NO 21980, SP7

    UniProt

    P07766

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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