Recombinant DLL4 抗体
Quick Overview for Recombinant DLL4 抗体 (ABIN7543202)
抗原
See all DLL4 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-DLL4 [61B], Rabbit IgG, kappa
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特异性
- This antibody is specific for the EGF-like 3 domain of Dll4.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing mice with soluble human Dll4-His protein.
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亚型
- IgG kappa
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应用备注
- U87MG and HT29 cells were immune-stained with this antibody (Zhou et al, 2015, pmid:26288060). This antibody is used for immunohistochemistry on U87MG and HT29 (Zhou et al, 2015, pmid:26288060). The 64Cu-chelator DOTA conjugated version of this antibody was used for the positron-emission tomography (PET) imaging of human glioblastoma and colorectal cancer xenografts (Zhou et al, 2015, pmid:26288060). This antibody was used for immunohistochemistry on spheroids and monolayers cells (US7906116). ELISA was performed with this antibody on Dll4 truncation mutants (US7906116). This antibody is able to block the Dll4-Notch1 interaction (US7906116).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- DLL4 (delta-Like 4 (DLL4))
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别名
- DLL4
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背景
- Delta-like protein 4, Drosophila Delta homolog 4, Delta4
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UniProt
- Q9NR61
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途径
- Notch Signaling
抗原
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