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Recombinant DLL4 抗体

This anti-DLL4 antibody is a 兔 Chimeric antibody detecting DLL4 in ELISA, IHC, IF 和 BP. Suitable for 人.
产品编号 ABIN7543202
发货至: 中国

Quick Overview for Recombinant DLL4 抗体 (ABIN7543202)

抗原

See all DLL4 抗体
DLL4 (delta-Like 4 (DLL4))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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Chimeric

标记

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This DLL4 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Blocking Peptide (BP)

克隆位点

61B
  • 原理

    Anti-DLL4 [61B], Rabbit IgG, kappa

    特异性

    This antibody is specific for the EGF-like 3 domain of Dll4.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2a

    纯化方法

    Protein A affinity purified

    免疫原

    The original antibody was generated by immunizing mice with soluble human Dll4-His protein.

    亚型

    IgG kappa
  • 应用备注

    U87MG and HT29 cells were immune-stained with this antibody (Zhou et al, 2015, pmid:26288060). This antibody is used for immunohistochemistry on U87MG and HT29 (Zhou et al, 2015, pmid:26288060). The 64Cu-chelator DOTA conjugated version of this antibody was used for the positron-emission tomography (PET) imaging of human glioblastoma and colorectal cancer xenografts (Zhou et al, 2015, pmid:26288060). This antibody was used for immunohistochemistry on spheroids and monolayers cells (US7906116). ELISA was performed with this antibody on Dll4 truncation mutants (US7906116). This antibody is able to block the Dll4-Notch1 interaction (US7906116).

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    DLL4 (delta-Like 4 (DLL4))

    别名

    DLL4

    背景

    Delta-like protein 4, Drosophila Delta homolog 4, Delta4

    UniProt

    Q9NR61

    途径

    Notch Signaling
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