SYN1 抗体 (pSer62, pSer67)
Quick Overview for SYN1 抗体 (pSer62, pSer67) (ABIN7540655)
抗原
See all SYN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer62, pSer67
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Supplier Product No.
- 612-401-e33
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Supplier
- Rockland
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原理
- Synapsin I phospho S62 + S67 Antibody
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交叉反应 (详细)
- Anti-Synapsin I pS62/67 antibody is directed against rat Synapsin I.
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纯化方法
- Synapsin I pS62/67 antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- Anti-Synapsin I pS62/pS67 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser62/67 of Synapsin I protein.
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亚型
- IgG
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应用备注
- Optional[Neutralization_Dilution]: 1:1000
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说明
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Suggested Applications: Titrated value sufficient to run approximately 10 mini blots.
Anti-Synapsin I pS62/pS67 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 78 kDa in size corresponding to synapsin I doublet phosphorylated at Ser62/67 in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- SYN1 (Synapsin I (SYN1))
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别名
- Syn1
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背景
- Synapsin I, SYN1, Synapsin-1,Synapsin I pS62/67 antibody detects phosphorylated Synapsin I, which plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Ser 549 along with Ser 62 and Ser 67 are the sites of Synapsin I that are phosphorylated by MAP kinase. Anti-Synapsin I pS62/pS67 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
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基因ID
- 24949
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NCBI登录号
- NP_001104252
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UniProt
- P09951
抗原
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