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Caspase 12 抗体 (Internal Region)

This anti-Caspase 12 antibody is a 兔 多克隆 antibody detecting Caspase 12 in WB, ELISA, IF 和 FM. Suitable for 小鼠.
Rockland
产品编号 ABIN7540611
Supplier Product No.: 600-401-mj3
发货至: 中国

Quick Overview for Caspase 12 抗体 (Internal Region) (ABIN7540611)

抗原

See all Caspase 12 (CASP12) 抗体
Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))

适用

  • 63
  • 48
  • 31
小鼠

宿主

  • 90
  • 2

克隆类型

  • 90
  • 2
多克隆

标记

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This Caspase 12 antibody is un-conjugated

应用范围

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  • 12
  • 7
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Fluorescence Microscopy (FM)
  • 抗原表位

    • 16
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    • 8
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    • 4
    • 3
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    Internal Region

    Supplier Product No.

    600-401-mj3

    Supplier

    Rockland

    原理

    Caspase 12 Antibody

    交叉反应 (详细)

    This affinity purified antibody is directed against mouse Caspase 12.

    纯化方法

    The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

    过滤

    Sterile filtered

    免疫原

    Anti-Caspase 12 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of mouse Caspase 12 conjugated to Keyhole Limpet Hemocyanin (KLH).

    亚型

    IgG
  • 应用备注

    ELISA_Dilution: 1:10,000 - 1:50,000

    IF_Microscopy_Dilution: 15 μg/mL

    Western_Blot_Dilution: 5 μg/mL

    说明

    Anti-Caspase 12 Antibody has been tested in ELISA, IF, and WB.  Positive control used: NIH/3T3 and PC-12 lysates in Western Blot and NIH/3T3 in Immunofluorescence.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))

    别名

    Casp12

    背景

    Rabbit Anti-Caspase 12 Antibody, Caspase 12 pseudogene 1, Casp12, Casp-12, CASP12P1,Casp12 (Caspase 12 (Gene/Pseudogene)) has no protease activity. It may reduce cytokine release in response to bacterial lipopolysaccharide during infections. Caspase 12 reduces activation of NF-kappa-B in response to TNF. Caspases (cysteinyl aspartate proteases) are involved in the signaling pathways of apoptosis, necrosis and inflammation. These enzymes can be divided into initiators and effectors. The initiator isoforms are activated by, and interact with, upstream adaptor molecules. Anti-Caspase 12 Antibody is useful for researchers interested in Amyotrophic lateral sclerosis (ALS), ATP synthesis, and Apoptosis research.

    基因ID

    12364

    NCBI登录号

    NP_033938

    UniProt

    O08736

    途径

    Apoptosis, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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