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MAPK14 抗体 (pThr180, pTyr182)

This 兔 多克隆 antibody specifically detects MAPK14 in WB 和 IHC. It exhibits reactivity toward 大鼠.
Rockland
产品编号 ABIN7540583
Supplier Product No.: 600-401-c90
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MAPK14 抗体 (pThr180, pTyr182) (ABIN7540583)

抗原

See all MAPK14 抗体
MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This MAPK14 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    pThr180, pTyr182

    Supplier Product No.

    600-401-c90

    Supplier

    Rockland

    原理

    p38 MAPK phospho T180/phospho Y182 Antibody

    交叉反应 (详细)

    antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.

    纯化方法

    Anti-p38 MAPK pT180/pY182 Antibody is directed against p38 MAPK phosphorylated at T180 and Y182.

    免疫原

    Anti-p38 MAPK pT180/pY182 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Thr180/Tyr182.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry_Dilution: 1:250

    Western_Blot_Dilution: 1:1000

    Other: User Optimized

    说明

    Anti-p38 MAPK pT180/pY182 Antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 39kDa in size corresponding to p38 MAPK protein phosphorylated at Thr180/Tyr182 in the appropriate cell lysate or extract.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

    别名

    Mapk14

    背景

    Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, CRK1, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha,p38 MAPK pT180/pY182 Antibody detects phosphorylated p38 MAPK protein. The three Mitogen-Activated Protein Kinases (MAPKs) are evolutionarily conserved protein kinases that control a vast array of cellular processes. p38 MAPK is one of these kinases and it is activated by both inflammatory cytokines and by stress. The p38 MAPK is thought to be particularly important in diseases like asthma and autoimmunity but it also plays important roles in the stress response of the nervous system. Like the other MAPKs, p38 is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182. Anti-p38 MAPK pT180/pY182 Antibody is ideal for investigators involved in Signal Transduction and Apoptosis research.

    基因ID

    70496

    NCBI登录号

    NM_031020

    UniProt

    P70618

    途径

    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins
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