Gelsolin 抗体
Quick Overview for Gelsolin 抗体 (ABIN7540497)
抗原
See all Gelsolin (GSN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 200-301-p37
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Supplier
- Rockland
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原理
- Gelsolin Antibody
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交叉反应 (详细)
- This product reacts with human and rabbit.
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纯化方法
- Anti-Gelsolin antibody was purified from mouse ascites by protein A chromatography.
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免疫原
- Gelsolin antibody was produced in mice by repeated immunizations with human plasma gelsolin.
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亚型
- IgG1
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应用备注
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ELISA_Dilution: 1:10,000
Immunohistochemistry_Dilution: 1:100-1:500
Western_Blot_Dilution: 0.5-1 μg/mL
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说明
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Anti-Gelsolin is tested for Immunohistochemistry -P, -F and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~85.7 kDa corresponding to the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution_Buffer: Neutral PBS
Reconstitution_Volume: 1.0 mL
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缓冲液
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Buffer: 1.2 % sodium acetate
Stabilizer: 2 mg BSA
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- Gelsolin (GSN)
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别名
- GSN
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背景
- AGEL, ADF, Brevin, Actin-depolymerizing factor,Gelsolin, a protein of leukocytes, platelets, and other cells, severs actin filaments in the presence of submicromolar calcium, thereby solating cytoplasmic actin gels. A gelsolin variant with 23 more N-terminal amino acids is a plasma component probably involved in the clearance of actin, the most abundant human protein, from the circulation. Gelsolin is located in 9q34. Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain. This antibody is suitable for researchers interested in cell research and cytoskeletal signaling research.
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基因ID
- 2934
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NCBI登录号
- NP_000168
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UniProt
- P06396
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途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
抗原
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