PODXL 抗体 (PE)
Quick Overview for PODXL 抗体 (PE) (ABIN7540464)
抗原
See all PODXL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu PODXL PE
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特异性
- The mouse monoclonal antibody PcMab-47 recognizes a glycosylation-dependent epitope (aa 207-210) on human PODXL, a highly glycosylated transmembrane glycoprotein expressed above all in many types of cancer tissues, and on embryonic stem cells.
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- recombinant PODXL ectodomain
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亚型
- IgG1 kappa
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应用备注
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- PODXL (Podocalyxin-Like (PODXL))
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别名
- PODXL
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背景
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NCBI Full Gene Name: podocalyxin like
Description: PODXL is a highly glycosylated sialomucin, which is expressed in many types of tumors, as well as it is a well known marker of embryonic stem cells. Overexpression of PODXL is an independent predictor of cancer progression, metastasis, and poor outcome. PODXL promotes tumor growts and invasiveness, and is a potential target for antibody therapy.
Other names: PCLP-1, Gp200, podocalyxin like
Gene name: PODXL
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基因ID
- 5420
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UniProt
- O00592
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途径
- Tube Formation
抗原
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