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CD70 抗体 (FITC)

This 小鼠 单克隆 antibody specifically detects CD70 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7540451
发货至: 中国
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Room 801-803
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Quick Overview for CD70 抗体 (FITC) (ABIN7540451)

抗原

See all CD70 抗体
CD70 (CD70 Molecule (CD70))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD70 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

Ki-24
  • 原理

    Anti-Hu CD70 FITC

    特异性

    The mouse monoclonal antibody Ki-24 recognizes an extracellular epitope of CD70, an approximately 50 kDa type II transmembrane glycoprotein expressed on activated lymphocytes and some B cell leukemias.

    纯化方法

    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    human L428 cell line

    亚型

    IgG3 kappa
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    CD70 (CD70 Molecule (CD70))

    别名

    CD70

    背景

    NCBI Full Gene Name: CD70 Molecule

    Description: CD70, also known as TNFSF7 or CD27L, is a 50 kDa type II transmembrane glycoprotein of the TNF superfamily. It is expressed mainly on activated lymphocytes, including NK cells, and forms trimeric structure. CD70 plays a role in T-cell activation, proliferation and differentiation, in enhancing the generation of cytolytic T cells, and in long-term maintenance of T cell memory. It is also involved in B cell differentiation induced by activated plasmacytoid dendritic cells, which also express CD70.

    Other names: CD27L, TNFSF7, CD27 ligand, TNLG8A

    Gene name: CD70

    基因ID

    970

    UniProt

    P32970

    途径

    Cancer Immune Checkpoints
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