CD70 抗体 (APC)
Quick Overview for CD70 抗体 (APC) (ABIN7540450)
抗原
See all CD70 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD70 APC
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特异性
- The mouse monoclonal antibody Ki-24 recognizes an extracellular epitope of CD70, an approximately 50 kDa type II transmembrane glycoprotein expressed on activated lymphocytes and some B cell leukemias.
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纯化方法
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- human L428 cell line
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亚型
- IgG3 kappa
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anti-CD70 Molecule (CD70) (AA 39-193) antibody
CD70 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) antibodyCD70 适用: 人 FACS 宿主: 小鼠 Monoclonal Ki-24 unconjugated
anti-CD70 Molecule (CD70) antibody (PE)CD70 适用: 人 FACS 宿主: 小鼠 Monoclonal Ki-24 PE
anti-CD70 Molecule (CD70) (AA 47-191) antibodyCD70 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) antibodyCD70 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) (AA 1-193) antibodyCD70 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) antibodyCD70 适用: 人 WB, FACS 宿主: 兔 Monoclonal unconjugated
anti-CD70 Molecule (CD70) (AA 72-101) antibodyCD70 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) (AA 64-192) antibodyCD70 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) antibody (PerCP-Cy5.5)CD70 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal FR70 PerCP-Cy5.5
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- CD70 (CD70 Molecule (CD70))
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别名
- CD70
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背景
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NCBI Full Gene Name: CD70 Molecule
Description: CD70, also known as TNFSF7 or CD27L, is a 50 kDa type II transmembrane glycoprotein of the TNF superfamily. It is expressed mainly on activated lymphocytes, including NK cells, and forms trimeric structure. CD70 plays a role in T-cell activation, proliferation and differentiation, in enhancing the generation of cytolytic T cells, and in long-term maintenance of T cell memory. It is also involved in B cell differentiation induced by activated plasmacytoid dendritic cells, which also express CD70.
Other names: CD27L, TNFSF7, CD27 ligand, TNLG8A
Gene name: CD70
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基因ID
- 970
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UniProt
- P32970
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途径
- Cancer Immune Checkpoints
抗原
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