Recombinant CD31 抗体 (Extracellular Domain) (Atto 647N)
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- 抗原 See all CD31 (PECAM1) 抗体
- CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
- 抗体类型
- Recombinant Antibody
- 片段
- single-domain Antibody (sdAb)
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抗原表位
- Extracellular Domain
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适用
- 小鼠
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宿主
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Alpaca
- Expression System
- E.coli
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克隆类型
- Multiclonal
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标记
- This CD31 antibody is conjugated to Atto 647N
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应用范围
- Immunofluorescence (IF), Immunofluorescence (fixed cells) (IF/ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 原理
- Alpaca anti-mouse CD31 VHH is a carefully developed and validated nanobody (single-domain antibody) binding to human CD31 (PECAM-1) highly suitabe for tissue staining.
- 品牌
- LIMAAbody®
- 特异性
- Detects endogenous levels of total murine CD31 protein.
- 交叉反应 (详细)
- not analysed
- 产品特性
- VHH protein tag: C-terminal (6x) His-Tag
- 纯化方法
- Affinity-purified antibody fragment.
- 免疫原
- Recombinant protein containing the extracellular domain of murine CD31 protein.
- 克隆位点
- 3ELC120-3ELC140-3ELC105-3ELC143
- Top Product
- Discover our top product PECAM1 Primary Antibody
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- 应用备注
- Immunofluorescence: 10 μg/mL (frozen sections), 1 μg/mL (cell culture), 20 μg/mL (wholemount)
- 说明
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VHH protein tag: C-terminal (6x) His-Tag
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, pH 7.4, 0.02% sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Upon receipt store at 4°C. Stable for 6 months. Do not freeze.
- 有效期
- 6 months
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- 抗原
- CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
- 别名
- CD31 (PECAM1 产品)
- 背景
- CD31, also known as PECAM-1, is an adhesion molecule and is expressed on endothelial cells at intercellular junctions and various T cell subsets. It shows altered expression levels in arterial, venous and lymphatic vessels. It is also found to a lesser extent on platelets, as well as most other leukocytes including monocytes and neutrophils. CD31 facilitates homotypic binding to itself, as well as heterotypic binding to the leukocyte integrin alpha V beta III. CD31 plays a crucial role in facilitating the transendothelial migration of leukocytes through the intercellular junctions of vascular endothelial cells. It is one of key regulatory molecules in vascular system.
- 分子量
- 81 kDa
- NCBI登录号
- NP_033868
- UniProt
- Q08481
- 途径
- Regulation of Actin Filament Polymerization
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