APC 抗体 (AA 2644-2843)
Quick Overview for APC 抗体 (AA 2644-2843) (ABIN7539857)
抗原
See all APC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 2644-2843
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原理
- APC Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human APC (AA: 2644-2843) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- APC (Adenomatous Polyposis Coli (APC))
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别名
- APC
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背景
- This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
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分子量
- 311.6 kDa
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基因ID
- 324
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UniProt
- P25054
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途径
- WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
抗原
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