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APC 抗体 (AA 2644-2843)

This anti-APC antibody is a 小鼠 单克隆 antibody detecting APC in ELISA 和 FACS. Suitable for 人.
产品编号 ABIN7539857
发货至: 中国

Quick Overview for APC 抗体 (AA 2644-2843) (ABIN7539857)

抗原

See all APC 抗体
APC (Adenomatous Polyposis Coli (APC))

适用

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宿主

  • 102
  • 18
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小鼠

克隆类型

  • 92
  • 34
单克隆

标记

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This APC antibody is un-conjugated

应用范围

  • 71
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ELISA, Flow Cytometry (FACS)

克隆位点

1F7G2
  • 抗原表位

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    AA 2644-2843

    原理

    APC Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human APC (AA: 2644-2843) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    APC (Adenomatous Polyposis Coli (APC))

    别名

    APC

    背景

    This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

    分子量

    311.6 kDa

    基因ID

    324

    UniProt

    P25054

    途径

    WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
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