MAP2K5 抗体 (AA 63-180)
Quick Overview for MAP2K5 抗体 (AA 63-180) (ABIN7539842)
抗原
See all MAP2K5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 63-180
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原理
- MAP2K5 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human MAP2K5 (AA: 63-180) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
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别名
- MAP2K5
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背景
- The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
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分子量
- 50 kDa
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UniProt
- Q13163
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway
抗原
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