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beta Arrestin 1 抗体 (AA 89-268)

The 小鼠 单克隆 anti-beta Arrestin 1 antibody is suitable to detect beta Arrestin 1 in samples from 人. It has been validated for ELISA.
产品编号 ABIN7539841
发货至: 中国
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Quick Overview for beta Arrestin 1 抗体 (AA 89-268) (ABIN7539841)

抗原

See all beta Arrestin 1 (ARRB1) 抗体
beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

适用

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  • 1
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宿主

  • 98
  • 9
  • 1
小鼠

克隆类型

  • 78
  • 30
单克隆

标记

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  • 1
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This beta Arrestin 1 antibody is un-conjugated

应用范围

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ELISA

克隆位点

4E11B1
  • 抗原表位

    • 22
    • 13
    • 8
    • 5
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    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    AA 89-268

    原理

    ARRB1 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human ARRB1 (AA: 89-268) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

    别名

    ARRB1

    背景

    Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.

    分子量

    47 kDa

    UniProt

    P49407

    途径

    Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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