RAD23B 抗体
Quick Overview for RAD23B 抗体 (ABIN7539777)
抗原
See all RAD23B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- RAD23B Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human RAD23B expressed in E. Coli.
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亚型
- IgG1
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应用备注
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FCM: 1/200 - 1/400
ICC: 1/100 - 1/400
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限制
- 仅限研究用
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- RAD23B (RAD23 Homolog B (RAD23B))
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别名
- RAD23B
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背景
- The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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分子量
- 43.2 kDa
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基因ID
- 5887
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UniProt
- P54727
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途径
- DNA Damage Repair
抗原
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